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The albumin-exendin-4 recombinant protein E2HSA improves glycemic control and β-cell function in spontaneous diabetic KKAy mice

BACKGROUND: E2HSA is a genetic fusion protein that consists of two tandem exendin-4 molecules that are covalently bonded to recombinant human serum albumin via a peptide linker. Previous studies have demonstrated that E2HSA significantly decreased blood glucose levels, improved β-cell function and p...

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Detalles Bibliográficos
Autores principales:	Li, Caina, Hou, Shaocong, Liu, Shuainan, Huan, Yi, Sun, Sujuan, Liu, Quan, Shen, Zhufang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477380/ https://www.ncbi.nlm.nih.gov/pubmed/28629388 http://dx.doi.org/10.1186/s40360-017-0143-8

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