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Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα
Inflammation and thrombosis occur together in many diseases. The leukocyte integrin Mac-1 (also known as integrin α(M)β(2), or CD11b/CD18) is crucial for leukocyte recruitment to the endothelium, and Mac-1 engagement of platelet GPIbα is required for injury responses in diverse disease models. Howev...
Autores principales: | Wang, Yunmei, Gao, Huiyun, Shi, Can, Erhardt, Paul W., Pavlovsky, Alexander, A. Soloviev, Dmitry, Bledzka, Kamila, Ustinov, Valentin, Zhu, Liang, Qin, Jun, Munday, Adam D., Lopez, Jose, Plow, Edward, Simon, Daniel I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477519/ https://www.ncbi.nlm.nih.gov/pubmed/28555620 http://dx.doi.org/10.1038/ncomms15559 |
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