SRT1720 promotes survival of aged human mesenchymal stem cells via FAIM: a pharmacological strategy to improve stem cell-based therapy for rat myocardial infarction

SIRT1 has been proved to rejuvenate and improve the therapeutic efficacy of aged rat mesenchymal stem cells (MSCs). Herein, we investigate the protective effect of pretreatment with SIRT1 activator SRT1720 on aged human MSCs (hMSCs). The optimized pretreatment condition for aged hMSCs was determined...

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Detalles Bibliográficos
Autores principales: Liu, Xianbao, Hu, Dexing, Zeng, Zhiru, Zhu, Wei, Zhang, Na, Yu, Hong, Chen, Han, Wang, Kan, Wang, Yingchao, Wang, Lengmei, Zhao, Jing, Zhang, Ling, Wu, Rongrong, Hu, Xinyang, Wang, Jian'an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477573/
https://www.ncbi.nlm.nih.gov/pubmed/28383554
http://dx.doi.org/10.1038/cddis.2017.107

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