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cPLA2α mediates TGF-β-induced epithelial–mesenchymal transition in breast cancer through PI3k/Akt signaling

A high incidence of tumor recurrence and metastasis has been reported in breast cancer patients; nevertheless, the underlying molecular mechanisms are largely unknown. Epithelial–mesenchymal transition (EMT), which is induced by transforming growth factor-β (TGF-β), has been implicated in tumorigene...

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Detalles Bibliográficos
Autores principales: Chen, Lu, Fu, Hui, Luo, Yi, Chen, Liwei, Cheng, Runfen, Zhang, Ning, Guo, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477578/
https://www.ncbi.nlm.nih.gov/pubmed/28383549
http://dx.doi.org/10.1038/cddis.2017.152