Cargando…

Extracellular cystatin SN and cathepsin B prevent cellular senescence by inhibiting abnormal glycogen accumulation

Cystatin SN (CST1), a known inhibitor of cathepsin B (CatB), has important roles in tumor development. Paradoxically, CatB is a member of the cysteine cathepsin family that acts in cellular processes, such as tumor development and invasion. However, the relationship between CST1 and CatB, and their...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oh, Sang-Seok, Park, Soojong, Lee, Ki-Won, Madhi, Hamadi, Park, Sae Gwang, Lee, Hee Gu, Cho, Yong-Yeon, Yoo, Jiyun, Dong Kim, Kwang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477579/ https://www.ncbi.nlm.nih.gov/pubmed/28383558 http://dx.doi.org/10.1038/cddis.2017.153

Ejemplares similares

Cystatin SN neutralizes the inhibitory effect of cystatin C on cathepsin B activity
por: Kim, J-T, et al.
Publicado: (2013)

Cordycepin Resensitizes T24R2 Cisplatin-Resistant Human Bladder Cancer Cells to Cisplatin by Inactivating Ets-1 Dependent MDR1 Transcription
por: Oh, Sang-Seok, et al.
Publicado: (2020)

Posttranslational Processing and Modification of Cathepsins and Cystatins
por: Katunuma, Nobuhiko
Publicado: (2010)

Plasma Cathepsin S and Cathepsin S/Cystatin C Ratios Are Potential Biomarkers for COPD
por: Nakajima, Takahiro, et al.
Publicado: (2016)

NDRG2 contributes to cisplatin sensitivity through modulation of BAK-to-Mcl-1 ratio
por: Park, Soojong, et al.
Publicado: (2018)

Research progress of cystatin SN in cancer
por: Liu, Yanfang, et al.
Publicado: (2019)

Cathepsins and their endogenous inhibitors cystatins: expression and modulation in multiple sclerosis
por: Haves-Zburof, Dana, et al.
Publicado: (2011)

Expression of Cathepsin B and Cystatin A in Oral Lichen Planus
por: Bangsuwan, Pear, et al.
Publicado: (2021)

Internalization of Exogenous Cystatin F Supresses Cysteine Proteases and Induces the Accumulation of Single-chain Cathepsin L by Multiple Mechanisms
por: Colbert, Jeff D., et al.
Publicado: (2011)

Cathepsins B, L and cystatin C in cyst fluid of ovarian tumors
por: Kolwijck, Eva, et al.
Publicado: (2009)

Macrophage Derived Cystatin B/Cathepsin B in HIV Replication and Neuropathogenesis
por: Rivera, Linda E., et al.
Publicado: (2014)

Cystatin C and Cystatin SN As Possible Soluble Tumor Markers in Malignant Uveal Melanoma
por: Dikovskaya, Maria A., et al.
Publicado: (2021)

Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis
por: Hamilton, Garth, et al.
Publicado: (2008)

Elevated Serum Cystatin C and Decreased Cathepsin S/Cystatin C Ratio Are Associated with Severe Peripheral Arterial Disease and Polyvascular Involvement
por: Nagy, Előd Ernő, et al.
Publicado: (2022)

Cystatin SN Upregulation in Patients with Seasonal Allergic Rhinitis
por: Imoto, Yoshimasa, et al.
Publicado: (2013)

Molecular determinants of improved cathepsin B inhibition by new cystatins obtained by DNA shuffling
por: Valadares, Napoleão F, et al.
Publicado: (2010)

High levels of cathepsin D and cystatin B are associated with increased risk of coronary events
por: Gonçalves, Isabel, et al.
Publicado: (2016)

Cystatin B, cathepsin L and D related to surrogate markers for cardiovascular disease in children
por: Dencker, Magnus, et al.
Publicado: (2017)

Cathepsin B as a potential cystatin M/E target in the mouse hair follicle
por: Oortveld, Merel A. W., et al.
Publicado: (2017)

Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer
por: Oh, Byung Moo, et al.
Publicado: (2017)

Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer
por: Oh, Byung Moo, et al.
Publicado: (2017)

Glycogen overload transforms the liver: Accumulated glycogen drives liver tumorigenesis
por: Li, Peiyi, et al.
Publicado: (2022)

Regulation of split anergy in natural killer cells by inhibition of cathepsins C and H and cystatin F
por: Magister, Špela, et al.
Publicado: (2015)

Cystatin C as a p53‐inducible apoptotic mediator that regulates cathepsin L activity
por: Mori, Jinichi, et al.
Publicado: (2016)

Disinhibition of Cathepsin C Caused by Cystatin F Deficiency Aggravates the Demyelination in a Cuprizone Model
por: Liang, Junjie, et al.
Publicado: (2016)

检测肺癌患者血清Cathepsin X及Cystatin C的临床意义
Publicado: (2013)

Cathepsin S Deficiency Results in Abnormal Accumulation of Autophagosomes in Macrophages and Enhances Ang II–Induced Cardiac Inflammation
por: Pan, Lili, et al.
Publicado: (2012)

Prognostic significance of cystatin SN associated nomograms in patients with colorectal cancer
por: Li, Taiyuan, et al.
Publicado: (2017)

Cystatin SN (CST1) as a Novel Salivary Biomarker of Periodontitis
por: Romano, Federica, et al.
Publicado: (2023)

Lysosomal glycogen accumulation in Pompe disease results in disturbed cytoplasmic glycogen metabolism
por: Canibano‐Fraile, Rodrigo, et al.
Publicado: (2022)

NDRG2 Sensitizes Myeloid Leukemia to Arsenic Trioxide via GSK3β–NDRG2–PP2A Complex Formation
por: Park, Soojong, et al.
Publicado: (2019)

Correction: Disinhibition of Cathepsin C Caused by Cystatin F Deficiency Aggravates the Demyelination in a Cuprizone Model
por: Liang, Junjie, et al.
Publicado: (2018)

Ectromelia virus suppresses expression of cathepsins and cystatins in conventional dendritic cells to efficiently execute the replication process
por: Bossowska-Nowicka, Magdalena, et al.
Publicado: (2019)

Salivary Tick Cystatin OmC2 Targets Lysosomal Cathepsins S and C in Human Dendritic Cells
por: Zavašnik-Bergant, Tina, et al.
Publicado: (2017)

Clinical application of simultaneous detection of cystatin C, cathepsin S, and IL-1 in classification of coronary artery disease
por: Yan, Ling, et al.
Publicado: (2017)

Clinical significance of serum cathepsin B and cystatin C levels and their ratio in the prognosis of patients with esophageal cancer
por: Yan, Yan, et al.
Publicado: (2017)

Modulation of Cystatin F in Human Macrophages Impacts Cathepsin-Driven Killing of Multidrug-Resistant Mycobacterium tuberculosis
por: Mandal, Manoj, et al.
Publicado: (2023)

Meibomian Gland Dysfunction Is Associated with Low Levels of Immunoglobulin Chains and Cystatin-SN
por: Muttuvelu, Danson Vasanthan, et al.
Publicado: (2023)

Plasma Cathepsin S and Cystatin C Levels and Risk of Abdominal Aortic Aneurysm: A Randomized Population–Based Study
por: Lv, Bing-Jie, et al.
Publicado: (2012)

Association of cathepsin B and cystatin C with an age-related pulmonary subclinical state in a healthy Chinese population
por: Wang, Nan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vh3fg62abjejg5ko3591ammc6q