miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice

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microRNAs were recently suggested to contribute to the pathogenesis of nonalcoholic fatty liver disease (NAFLD), a disease lacking specific pharmacological treatments. In that regard, nuclear receptors are arising as key molecular targets for the treatment of nonalcoholic steatohepatitis (NASH). Her...

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Detalles Bibliográficos
Autores principales: Rodrigues, Pedro M, Afonso, Marta B, Simão, André L, Carvalho, Catarina C, Trindade, Alexandre, Duarte, António, Borralho, Pedro M, Machado, Mariana V, Cortez-Pinto, Helena, Rodrigues, Cecília MP, Castro, Rui E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477590/
https://www.ncbi.nlm.nih.gov/pubmed/28406477
http://dx.doi.org/10.1038/cddis.2017.172
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