Withaferin-A kills cancer cells with and without telomerase: chemical, computational and experimental evidences

Maintenance of telomere length is the most consistent attribute of cancer cells. Tightly connected to their capacity to overcome replicative mortality, it is achieved either by activation of telomerase or an Alternative mechanism of Lengthening of Telomeres (ALT). Disruption of either of these mecha...

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Detalles Bibliográficos
Autores principales: Yu, Yue, Katiyar, Shashank P, Sundar, Durai, Kaul, Zeenia, Miyako, Eijiro, Zhang, Zhenya, Kaul, Sunil C, Reddel, Roger R, Wadhwa, Renu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477593/
https://www.ncbi.nlm.nih.gov/pubmed/28425984
http://dx.doi.org/10.1038/cddis.2017.33

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477593/
https://www.ncbi.nlm.nih.gov/pubmed/28425984
http://dx.doi.org/10.1038/cddis.2017.33

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