Inhibition of MMP-2 and MMP-9 decreases cellular migration, and angiogenesis in in vitro models of retinoblastoma

BACKGROUND: Retinoblastoma (Rb) is the most common primary intraocular tumor in children. Local treatment of the intraocular disease is usually effective if diagnosed early; however advanced Rb can metastasize through routes that involve invasion of the choroid, sclera and optic nerve or more broadl...

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Detalles Bibliográficos
Autores principales: Webb, Anderson H., Gao, Bradley T., Goldsmith, Zachary K., Irvine, Andrew S., Saleh, Nabil, Lee, Ryan P., Lendermon, Justin B., Bheemreddy, Rajini, Zhang, Qiuhua, Brennan, Rachel C., Johnson, Dianna, Steinle, Jena J., Wilson, Matthew W., Morales-Tirado, Vanessa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477686/
https://www.ncbi.nlm.nih.gov/pubmed/28633655
http://dx.doi.org/10.1186/s12885-017-3418-y

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