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Viral hepatitis in female sex workers using the Respondent-Driven Sampling
OBJECTIVE: To estimate the prevalence of hepatitis B virus and C virus infections and their genotypes and analyze the risk factors for the markers of exposure to hepatitis B virus in female sex workers in a region of intense sex trade. METHODS: This is a cross-sectional study performed with four hun...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Faculdade de Saúde Pública da Universidade de São Paulo
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477708/ https://www.ncbi.nlm.nih.gov/pubmed/28678904 http://dx.doi.org/10.1590/S1518-8787.2017051006540 |
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author | de Matos, Marcos André França, Divânia Dias da Silva Carneiro, Megmar Aparecida dos Santos Martins, Regina Maria Bringel Kerr, Lígia Regina Franco Sansigolo Caetano, Karlla Antonieta Amorim Pinheiro, Raquel Silva de Araújo, Lyriane Apolinário Mota, Rosa Maria Salani de Matos, Marcia Alves Dias Motta-Castro, Ana Rita Coimbra Teles, Sheila Araújo |
author_facet | de Matos, Marcos André França, Divânia Dias da Silva Carneiro, Megmar Aparecida dos Santos Martins, Regina Maria Bringel Kerr, Lígia Regina Franco Sansigolo Caetano, Karlla Antonieta Amorim Pinheiro, Raquel Silva de Araújo, Lyriane Apolinário Mota, Rosa Maria Salani de Matos, Marcia Alves Dias Motta-Castro, Ana Rita Coimbra Teles, Sheila Araújo |
author_sort | de Matos, Marcos André |
collection | PubMed |
description | OBJECTIVE: To estimate the prevalence of hepatitis B virus and C virus infections and their genotypes and analyze the risk factors for the markers of exposure to hepatitis B virus in female sex workers in a region of intense sex trade. METHODS: This is a cross-sectional study performed with four hundred and two female sex workers in Goiânia, Brazil. Data have been collected using the Respondent-Driven Sampling. The women have been interviewed and tested for markers of hepatitis B and C viruses. Positive samples have been genotyped. The data have been analyzed using the Respondent-Driven Sampling Analysis Tool, version 5.3, and Stata 11.0. RESULTS: The adjusted prevalence for hepatitis B virus and C virus were 17.1% (95%CI 11.6–23.4) and 0.7% (95%CI 0.1–1.5), respectively. Only 28% (95%CI 21.1–36.4) of the participants had serological evidence of vaccination against hepatitis B virus. Being older (> 40 years), being single, having a history of blood transfusion and use of cocaine, and ignoring the symptoms of sexually transmitted infections were associated with positivity for hepatitis B virus (p < 0.05). We have detected the subgenotype A1 of hepatitis B virus (n = 3) and the subtypes of hepatitis C virus 1a (n = 3) and 1b (n = 1). CONCLUSIONS: We can observe a low prevalence of infection of hepatitis B and C viruses in the studied population. However, the findings of the analysis of the risk factors show the need for more investment in prevention programs for sexual and drug-related behavior, as well as more efforts to vaccinate this population against hepatitis B. The genotypes of the hepatitis B virus and C virus identified are consistent with those circulating in Brazil. |
format | Online Article Text |
id | pubmed-5477708 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Faculdade de Saúde Pública da Universidade de São Paulo |
record_format | MEDLINE/PubMed |
spelling | pubmed-54777082017-06-27 Viral hepatitis in female sex workers using the Respondent-Driven Sampling de Matos, Marcos André França, Divânia Dias da Silva Carneiro, Megmar Aparecida dos Santos Martins, Regina Maria Bringel Kerr, Lígia Regina Franco Sansigolo Caetano, Karlla Antonieta Amorim Pinheiro, Raquel Silva de Araújo, Lyriane Apolinário Mota, Rosa Maria Salani de Matos, Marcia Alves Dias Motta-Castro, Ana Rita Coimbra Teles, Sheila Araújo Rev Saude Publica Original Articles OBJECTIVE: To estimate the prevalence of hepatitis B virus and C virus infections and their genotypes and analyze the risk factors for the markers of exposure to hepatitis B virus in female sex workers in a region of intense sex trade. METHODS: This is a cross-sectional study performed with four hundred and two female sex workers in Goiânia, Brazil. Data have been collected using the Respondent-Driven Sampling. The women have been interviewed and tested for markers of hepatitis B and C viruses. Positive samples have been genotyped. The data have been analyzed using the Respondent-Driven Sampling Analysis Tool, version 5.3, and Stata 11.0. RESULTS: The adjusted prevalence for hepatitis B virus and C virus were 17.1% (95%CI 11.6–23.4) and 0.7% (95%CI 0.1–1.5), respectively. Only 28% (95%CI 21.1–36.4) of the participants had serological evidence of vaccination against hepatitis B virus. Being older (> 40 years), being single, having a history of blood transfusion and use of cocaine, and ignoring the symptoms of sexually transmitted infections were associated with positivity for hepatitis B virus (p < 0.05). We have detected the subgenotype A1 of hepatitis B virus (n = 3) and the subtypes of hepatitis C virus 1a (n = 3) and 1b (n = 1). CONCLUSIONS: We can observe a low prevalence of infection of hepatitis B and C viruses in the studied population. However, the findings of the analysis of the risk factors show the need for more investment in prevention programs for sexual and drug-related behavior, as well as more efforts to vaccinate this population against hepatitis B. The genotypes of the hepatitis B virus and C virus identified are consistent with those circulating in Brazil. Faculdade de Saúde Pública da Universidade de São Paulo 2017-06-20 /pmc/articles/PMC5477708/ /pubmed/28678904 http://dx.doi.org/10.1590/S1518-8787.2017051006540 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles de Matos, Marcos André França, Divânia Dias da Silva Carneiro, Megmar Aparecida dos Santos Martins, Regina Maria Bringel Kerr, Lígia Regina Franco Sansigolo Caetano, Karlla Antonieta Amorim Pinheiro, Raquel Silva de Araújo, Lyriane Apolinário Mota, Rosa Maria Salani de Matos, Marcia Alves Dias Motta-Castro, Ana Rita Coimbra Teles, Sheila Araújo Viral hepatitis in female sex workers using the Respondent-Driven Sampling |
title | Viral hepatitis in female sex workers using the Respondent-Driven Sampling |
title_full | Viral hepatitis in female sex workers using the Respondent-Driven Sampling |
title_fullStr | Viral hepatitis in female sex workers using the Respondent-Driven Sampling |
title_full_unstemmed | Viral hepatitis in female sex workers using the Respondent-Driven Sampling |
title_short | Viral hepatitis in female sex workers using the Respondent-Driven Sampling |
title_sort | viral hepatitis in female sex workers using the respondent-driven sampling |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477708/ https://www.ncbi.nlm.nih.gov/pubmed/28678904 http://dx.doi.org/10.1590/S1518-8787.2017051006540 |
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