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Complete remission of IgA nephropathy after bone marrow transplantation for acute myeloid leukaemia

IgA nephropathy is the most common primary glomerulonephritis, but the pathogenesis of IgA nephropathy is still unclear. A 32-year-old woman was found to have IgA nephropathy and acute myeloid leukaemia. She was treated with allogenic bone marrow transplantation (BMT). After BMT, immunoflourescent s...

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Detalles Bibliográficos
Autores principales: Park, Eun-Kyung, Jeon, Jin-Seok, Noh, Hyun-Jin, Won, Jong-Ho, Park, Hee-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477877/
https://www.ncbi.nlm.nih.gov/pubmed/28657023
http://dx.doi.org/10.1093/ndtplus/sfn147
Descripción
Sumario:IgA nephropathy is the most common primary glomerulonephritis, but the pathogenesis of IgA nephropathy is still unclear. A 32-year-old woman was found to have IgA nephropathy and acute myeloid leukaemia. She was treated with allogenic bone marrow transplantation (BMT). After BMT, immunoflourescent staining of IgA and proteinuria disappeared. These findings suggest bone marrow cells are involved in the pathogenesis of IgA nephropathy. We herein report a case of complete remission of IgA nephropathy after BMT for acute myeloid leukaemia.