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DOT1L inhibitor improves early development of porcine somatic cell nuclear transfer embryos

Incomplete epigenetic reprogramming of the genome of donor cells causes poor early and full-term developmental efficiency of somatic cell nuclear transfer (SCNT) embryos. Previous research indicate that inhibition of the histone H3 K79 methyltransferase DOT1L, using a selective pharmacological inhib...

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Detalles Bibliográficos
Autores principales:	Tao, Jia, Zhang, Yu, Zuo, Xiaoyuan, Hong, Renyun, Li, Hui, Liu, Xing, Huang, Weiping, Cao, Zubing, Zhang, Yunhai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478106/ https://www.ncbi.nlm.nih.gov/pubmed/28632762 http://dx.doi.org/10.1371/journal.pone.0179436

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