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Over-expressing the soluble gp130-Fc does not ameliorate methionine and choline deficient diet-induced non alcoholic steatohepatitis in mice
Non-alcoholic steatohepatitis (NASH) is a liver disease with the potential to lead to cirrhosis and hepatocellular carcinoma. Interleukin-6 (IL-6) has been implicated in the pathogenesis of NASH, with the so-called IL-6 ‘trans-signaling’ cascade being responsible for the pro-inflammatory actions of...
Autores principales: | Kammoun, Helene L., Allen, Tamara Louise, Henstridge, Darren Colin, Kraakman, Michael James, Peijs, Lone, Rose-John, Stefan, Febbraio, Mark Anthony |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478123/ https://www.ncbi.nlm.nih.gov/pubmed/28632778 http://dx.doi.org/10.1371/journal.pone.0179099 |
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