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Molecular mechanism of DRP1 assembly studied in vitro by cryo-electron microscopy

Mitochondria are dynamic organelles that continually adapt their morphology by fusion and fission events. An imbalance between fusion and fission has been linked to major neurodegenerative diseases, including Huntington’s, Alzheimer’s, and Parkinson’s diseases. A member of the Dynamin superfamily, d...

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Detalles Bibliográficos
Autores principales: Basu, Kaustuv, Lajoie, Driss, Aumentado-Armstrong, Tristan, Chen, Jin, Koning, Roman I., Bossy, Blaise, Bostina, Mihnea, Sik, Attila, Bossy-Wetzel, Ella, Rouiller, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478127/
https://www.ncbi.nlm.nih.gov/pubmed/28632757
http://dx.doi.org/10.1371/journal.pone.0179397