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Molecular mechanism of DRP1 assembly studied in vitro by cryo-electron microscopy
Mitochondria are dynamic organelles that continually adapt their morphology by fusion and fission events. An imbalance between fusion and fission has been linked to major neurodegenerative diseases, including Huntington’s, Alzheimer’s, and Parkinson’s diseases. A member of the Dynamin superfamily, d...
Autores principales: | Basu, Kaustuv, Lajoie, Driss, Aumentado-Armstrong, Tristan, Chen, Jin, Koning, Roman I., Bossy, Blaise, Bostina, Mihnea, Sik, Attila, Bossy-Wetzel, Ella, Rouiller, Isabelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478127/ https://www.ncbi.nlm.nih.gov/pubmed/28632757 http://dx.doi.org/10.1371/journal.pone.0179397 |
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