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Selective cyclooxygenase inhibition by SC-560 improves hepatopulmonary syndrome in cirrhotic rats
OBJECTIVE: Hepatopulmonary syndrome (HPS) is characterized by hypoxia in patients with chronic liver disease. The mechanism of HPS includes pulmonary vasodilatation, inflammation, and angiogenesis. Prostaglandins synthesized by cyclooxygenases (COX) participate in vascular responsiveness, inflammati...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478154/ https://www.ncbi.nlm.nih.gov/pubmed/28632747 http://dx.doi.org/10.1371/journal.pone.0179809 |