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Selective cyclooxygenase inhibition by SC-560 improves hepatopulmonary syndrome in cirrhotic rats

OBJECTIVE: Hepatopulmonary syndrome (HPS) is characterized by hypoxia in patients with chronic liver disease. The mechanism of HPS includes pulmonary vasodilatation, inflammation, and angiogenesis. Prostaglandins synthesized by cyclooxygenases (COX) participate in vascular responsiveness, inflammati...

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Detalles Bibliográficos
Autores principales:	Chang, Ching-Chih, Lee, Wen-Shin, Hsieh, Hsian-Guey, Chuang, Chiao-Lin, Huang, Hui-Chun, Lee, Fa-Yauh, Lee, Shou-Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478154/ https://www.ncbi.nlm.nih.gov/pubmed/28632747 http://dx.doi.org/10.1371/journal.pone.0179809

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