High-throughput Characterization of HIV-1 Reservoir Reactivation Using a Single-Cell-in-Droplet PCR Assay

Reactivation of latent viral reservoirs is on the forefront of HIV-1 eradication research. However, it is unknown if latency reversing agents (LRAs) increase the level of viral transcription from cells producing HIV RNA or harboring transcriptionally-inactive (latent) infection. We therefore develop...

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Detalles Bibliográficos
Autores principales: Yucha, Robert W., Hobbs, Kristen S., Hanhauser, Emily, Hogan, Louise E., Nieves, Wildaliz, Ozen, Mehmet O., Inci, Fatih, York, Vanessa, Gibson, Erica A., Thanh, Cassandra, Shafiee, Hadi, El Assal, Rami, Kiselinova, Maja, Robles, Yvonne P., Bae, Helen, Leadabrand, Kaitlyn S., Wang, ShuQi, Deeks, Steven G., Kuritzkes, Daniel R., Demirci, Utkan, Henrich, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478213/
https://www.ncbi.nlm.nih.gov/pubmed/28529033
http://dx.doi.org/10.1016/j.ebiom.2017.05.006

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