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Synergistic Cytotoxicity of Lenalidomide and Dexamethasone in Mantle Cell Lymphoma via Cereblon-dependent Targeting of the IL-6/STAT3/PI3K Axis
At our center, relapsed mantle cell lymphoma (MCL) can be treated with maintenance therapy composed of consecutive low-dose lenalidomide and short-term, high-dose dexamethasone (LD regimen), which achieves good responses (longer overall survival and progression-free survival) and low toxicity. Cereb...
Autores principales: | Ma, Jiexian, Wu, Kefei, Bai, Weiya, Cui, Xiaoxian, Chen, Yan, Xie, Youhua, Xie, Yanhui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478233/ https://www.ncbi.nlm.nih.gov/pubmed/28529032 http://dx.doi.org/10.1016/j.ebiom.2017.04.037 |
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