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Activation of PKCα and PI3K Kinases in Hypertrophic and Nodular Port Wine Stain Lesions

Port wine stain (PWS) is a congenital, progressive vascular malformation. Many patients with PWS develop hypertrophy and discrete nodularity during their adult life, but the mechanism(s) remain incompletely understood. In this study, we attempted to investigate activation status of PKCα, PI3K, PDPK1...

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Detalles Bibliográficos
Autores principales: Yin, Rong, Gao, Lin, Tan, Wenbin, Guo, Wei, Zhao, Tao, Nelson, Jhon Stuart, Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Journal of Dermatopathology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478501/
https://www.ncbi.nlm.nih.gov/pubmed/28030367
http://dx.doi.org/10.1097/DAD.0000000000000785