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LC-MS/MS quantification of sulfotransferases is better than conventional immunogenic methods in determining human liver SULT activities: implication in precision medicine

This study aims to determine whether enzyme activities are correlated with protein amounts and mRNA expression levels of five major human sulfotransferase (SULT) enzymes in 10 matched pericarcinomatous and hepatocellular carcinoma liver samples. The MRM UHPLC-MS/MS method, Western blot and RT-PCR we...

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Detalles Bibliográficos
Autores principales:	Xie, Cong, Yan, Tong-meng, Chen, Jia-mei, Li, Xiao-yan, Zou, Juan, Zhu, Li-jun, Lu, Lin-lin, Wang, Ying, Zhou, Fu-yuan, Liu, Zhong-qiu, Hu, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478605/ https://www.ncbi.nlm.nih.gov/pubmed/28634336 http://dx.doi.org/10.1038/s41598-017-04202-w

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