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A small-molecule DS44170716 inhibits Ca(2+)-induced mitochondrial permeability transition
Mitochondria are involved in a variety of physiological and pathological processes. Ca(2+) uptake is one of the important functions of the organelle for maintenance of cellular Ca(2+) homeostasis. In pathological conditions such as ischemia reperfusion injury, Ca(2+) overload into mitochondria induc...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478606/ https://www.ncbi.nlm.nih.gov/pubmed/28634393 http://dx.doi.org/10.1038/s41598-017-03651-7 |