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A small-molecule DS44170716 inhibits Ca(2+)-induced mitochondrial permeability transition

Mitochondria are involved in a variety of physiological and pathological processes. Ca(2+) uptake is one of the important functions of the organelle for maintenance of cellular Ca(2+) homeostasis. In pathological conditions such as ischemia reperfusion injury, Ca(2+) overload into mitochondria induc...

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Detalles Bibliográficos
Autores principales:	Kon, Naohiro, Satoh, Atsushi, Miyoshi, Naoki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478606/ https://www.ncbi.nlm.nih.gov/pubmed/28634393 http://dx.doi.org/10.1038/s41598-017-03651-7

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