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A Dynamical Model for Activating and Silencing the Mitotic Checkpoint
The spindle assembly checkpoint (SAC) is an evolutionarily conserved mechanism, exclusively sensitive to the states of kinetochores attached to microtubules. During metaphase, the anaphase-promoting complex/cyclosome (APC/C) is inhibited by the SAC but it rapidly switches to its active form followin...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478649/ https://www.ncbi.nlm.nih.gov/pubmed/28634351 http://dx.doi.org/10.1038/s41598-017-04218-2 |