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Expression of P301L-hTau in mouse MEC induces hippocampus-dependent memory deficit

Intracellular accumulation of abnormally phosphorylated tau in different types of neurons is a pathological characteristic of Alzheimer’s disease (AD). While tau modification and associated neuronal loss and hypometabolism start in the entorhinal cortex (EC) in early AD patients, the mechanism by wh...

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Detalles Bibliográficos
Autores principales:	Liu, Xinghua, Zeng, Kuan, Li, Mengzhu, Wang, Qun, Liu, Rong, Zhang, Bin, Wang, Jian-Zhi, Shu, Xiji, Wang, Xiaochuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478664/ https://www.ncbi.nlm.nih.gov/pubmed/28634382 http://dx.doi.org/10.1038/s41598-017-04305-4

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