A Novel Small Molecule GDNF Receptor RET Agonist, BT13, Promotes Neurite Growth from Sensory Neurons in Vitro and Attenuates Experimental Neuropathy in the Rat

Neuropathic pain caused by nerve damage is a common and severe class of chronic pain. Disease-modifying clinical therapies are needed as current treatments typically provide only symptomatic relief; show varying clinical efficacy; and most have significant adverse effects. One approach is targeting...

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Detalles Bibliográficos
Autores principales: Sidorova, Yulia A., Bespalov, Maxim M., Wong, Agnes W., Kambur, Oleg, Jokinen, Viljami, Lilius, Tuomas O., Suleymanova, Ilida, Karelson, Gunnar, Rauhala, Pekka V., Karelson, Mati, Osborne, Peregrine B., Keast, Janet R., Kalso, Eija A., Saarma, Mart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478727/
https://www.ncbi.nlm.nih.gov/pubmed/28680400
http://dx.doi.org/10.3389/fphar.2017.00365

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