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Effect of rosiglitazone on amyloid precursor protein processing and Aβ clearance in streptozotocin-induced rat model of Alzheimer’s disease

OBJECTIVE(S): Increasing evidence suggests that Alzheimer’s disease (AD) is associated with diabetes. Rosiglitazone, a peroxisome proliferator-activated receptor γ (PPAR-γ) agonist and anti-diabetic agent, may improve symptoms of AD. However, the underlying therapeutic potential of it has not been f...

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Detalles Bibliográficos
Autores principales: Wang, Li, Liu, Wei, Fan, Ying, Liu, Tingting, Yu, Chunjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478774/
https://www.ncbi.nlm.nih.gov/pubmed/28656081
http://dx.doi.org/10.22038/IJBMS.2017.8669