Cargando…

Effect of rosiglitazone on amyloid precursor protein processing and Aβ clearance in streptozotocin-induced rat model of Alzheimer’s disease

OBJECTIVE(S): Increasing evidence suggests that Alzheimer’s disease (AD) is associated with diabetes. Rosiglitazone, a peroxisome proliferator-activated receptor γ (PPAR-γ) agonist and anti-diabetic agent, may improve symptoms of AD. However, the underlying therapeutic potential of it has not been f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Li, Liu, Wei, Fan, Ying, Liu, Tingting, Yu, Chunjiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mashhad University of Medical Sciences 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478774/ https://www.ncbi.nlm.nih.gov/pubmed/28656081 http://dx.doi.org/10.22038/IJBMS.2017.8669

Ejemplares similares

Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts
por: Ehehalt, Robert, et al.
Publicado: (2003)

Processing of Mutant β-Amyloid Precursor Protein and the Clinicopathological Features of Familial Alzheimer’s Disease
por: Bi, Christopher, et al.
Publicado: (2019)

Heterogeneous Association of Alzheimer’s Disease-Linked Amyloid-β and Amyloid-β Protein Precursor with Synapses
por: Willén, Katarina, et al.
Publicado: (2017)

Failure of Alzheimer’s Mice Brain Resident Neural Precursor Cells in Supporting Microglia-Mediated Amyloid β Clearance
por: Lachish, Marva, et al.
Publicado: (2022)

Evidence for impaired amyloid β clearance in Alzheimer's disease
por: Wildsmith, Kristin R, et al.
Publicado: (2013)

Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's β-secretase
por: Scholefield, Zoe, et al.
Publicado: (2003)

Baicalein reduces β-amyloid and promotes nonamyloidogenic amyloid precursor protein processing in an Alzheimer’s disease transgenic mouse model
por: Zhang, She-Qing, et al.
Publicado: (2013)

Amyloid Precursor Protein and Alzheimer’s Disease
por: Orobets, Kseniia S., et al.
Publicado: (2023)

Clearance of amyloid β-protein and its role in the spreading of Alzheimer's disease pathology
por: Thal, Dietmar R.
Publicado: (2015)

TDP-43 and amyloid precursor protein processing: implications for Alzheimer’s disease
por: Hicks, David A.
Publicado: (2020)

Secretases Related to Amyloid Precursor Protein Processing
por: Liu, Xiaoling, et al.
Publicado: (2021)

Therapeutic Potential of Direct Clearance of the Amyloid-β in Alzheimer’s Disease
por: Kim, Dong Eun, et al.
Publicado: (2020)

Autophagy is involved in oligodendroglial precursor-mediated clearance of amyloid peptide
por: Li, Wenxia, et al.
Publicado: (2013)

Selectivity to amyloid-β precursor protein cleavage provides hope against Alzheimer's
por: Tomita, Taisuke, et al.
Publicado: (2011)

Soluble amyloid precursor protein β as blood-based biomarker of Alzheimer's disease
por: Perneczky, R, et al.
Publicado: (2013)

Altered β-Amyloid Precursor Protein Isoforms in Mexican Alzheimer’s Disease Patients
por: Sánchez-González, V. J., et al.
Publicado: (2006)

Insights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's disease
por: Dawkins, Edgar, et al.
Publicado: (2014)

Novel Anti-Alzheimer's Therapeutic Molecules Targeting Amyloid Precursor Protein Processing
por: Uddin, Md. Sahab, et al.
Publicado: (2020)

Localization and Processing of the Amyloid-β Protein Precursor in Mitochondria-Associated Membranes
por: Del Prete, Dolores, et al.
Publicado: (2016)

Divalent cation tolerance protein binds to β-secretase and inhibits the processing of amyloid precursor protein☆
por: Liu, Runzhong, et al.
Publicado: (2013)

Effects of Huanglian-Jie-Du-Tang and Its Modified Formula on the Modulation of Amyloid-β Precursor Protein Processing in Alzheimer's Disease Models
por: Durairajan, Siva Sundara Kumar, et al.
Publicado: (2014)

The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer’s disease
por: Kanekiyo, Takahisa, et al.
Publicado: (2014)

Copper binding to the Alzheimer’s disease amyloid precursor protein
por: Kong, Geoffrey K.-W., et al.
Publicado: (2007)

Modeling the β-secretase cleavage site and humanizing amyloid-beta precursor protein in rat and mouse to study Alzheimer’s disease
por: Serneels, Lutgarde, et al.
Publicado: (2020)

Mechanisms of Amyloid-β Peptide Clearance: Potential Therapeutic Targets for Alzheimer’s Disease
por: Yoon, Sang-Sun, et al.
Publicado: (2012)

Editorial: Clearance Pathways for Amyloid-β. Significance for Alzheimer's Disease and Its Therapy
por: Carare, Roxana O.
Publicado: (2017)

Amyloid precursor protein (APP) and amyloid β (Aβ) interact with cell adhesion molecules: Implications in Alzheimer’s disease and normal physiology
por: Pfundstein, Grant, et al.
Publicado: (2022)

Amyloid β Is Not the Major Factor Accounting for Impaired Adult Hippocampal Neurogenesis in Mice Overexpressing Amyloid Precursor Protein
por: Pan, Hongyu, et al.
Publicado: (2016)

Editorial on, “Amyloid-beta clearance in Alzheimer's disease”
por: Marr, Robert A.
Publicado: (2014)

Impacts of Membrane Biophysics in Alzheimer's Disease: From Amyloid Precursor Protein Processing to Aβ Peptide-Induced Membrane Changes
por: Askarova, Sholpan, et al.
Publicado: (2011)

Expression of the Tau Protein and Amyloid Protein Precursor Processing Genes in the CA3 Area of the Hippocampus in the Ischemic Model of Alzheimer’s Disease in the Rat
por: Pluta, Ryszard, et al.
Publicado: (2019)

The Intersection of NGF/TrkA Signaling and Amyloid Precursor Protein Processing in Alzheimer’s Disease Neuropathology
por: Canu, Nadia, et al.
Publicado: (2017)

Sodium rutin ameliorates Alzheimer’s disease–like pathology by enhancing microglial amyloid-β clearance
por: Pan, Rui-Yuan, et al.
Publicado: (2019)

Gamma frequency light flicker regulates amyloid precursor protein trafficking for reducing β‐amyloid load in Alzheimer's disease model
por: Shen, Qi, et al.
Publicado: (2022)

Amyloid precursor protein and amyloid precursor-like protein 2 in cancer
por: Pandey, Poomy, et al.
Publicado: (2016)

Amyloid precursor protein modulates β-catenin degradation
por: Chen, Yuzhi, et al.
Publicado: (2007)

β-Amyloid precursor protein (APP) and the human diseases
por: Nguyen, Khue Vu
Publicado: (2019)

Reduced CSF Water Influx in Alzheimer’s Disease Supporting the β-Amyloid Clearance Hypothesis
por: Suzuki, Yuji, et al.
Publicado: (2015)

URMC-099 facilitates amyloid-β clearance in a murine model of Alzheimer’s disease
por: Kiyota, Tomomi, et al.
Publicado: (2018)

Mutations of beta-amyloid precursor protein alter the consequence of Alzheimer’s disease pathogenesis
por: Li, Nuo-Min, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_2li129bhl0tu6aralhc82i0u66