Validation of a Liquid Chromatography-Tandem Mass Spectrometric Assay for Quantitative Analysis of Lenvatinib in Human Plasma

Toward conducting clinical pharmacokinetic studies of an antineoplastic agent, lenvatinib, we developed a liquid chromatography-tandem mass spectrometric assay for its quantitative analysis in human plasma. Analyte (lenvatinib) and internal standard (IS, propranolol) in the plasma were extracted by...

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Detalles Bibliográficos
Autores principales: Ogawa-Morita, Tomoko, Sano, Yoshiyuki, Okano, Tomoka, Fujii, Hirofumi, Tahara, Makoto, Yamaguchi, Masakazu, Minami, Hironobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478828/
https://www.ncbi.nlm.nih.gov/pubmed/28680445
http://dx.doi.org/10.1155/2017/2341876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478828/
https://www.ncbi.nlm.nih.gov/pubmed/28680445
http://dx.doi.org/10.1155/2017/2341876

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