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Generation of populations of antigen-specific cytotoxic T cells using DCs transfected with DNA construct encoding HER2/neu tumor antigen epitopes

BACKGROUND: Recent fundamental and clinical studies have confirmed the effectiveness of utilizing the potential of the immune system to remove tumor cells disseminated in a patient’s body. Cytotoxic T lymphocytes (CTLs) are considered the main effectors in cell-mediated antitumor immunity. Approache...

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Detalles Bibliográficos
Autores principales:	Kuznetsova, Maria, Lopatnikova, Julia, Khantakova, Julia, Maksyutov, Rinat, Maksyutov, Amir, Sennikov, Sergey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479015/ https://www.ncbi.nlm.nih.gov/pubmed/28633645 http://dx.doi.org/10.1186/s12865-017-0219-7

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