The role of NLRP3 inflammasome in 5-fluorouracil resistance of oral squamous cell carcinoma

BACKGROUND: 5-Fluorouracil (5-FU) is a widely used drug for the therapy of cancer. However, the chemoresistance of tumor cells to 5-FU usually limits its clinical effectiveness. In this study, we explored the role of NLRP3 inflammasome in 5-FU resistance of oral squamous cell carcinoma (OSCC). METHO...

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Detalles Bibliográficos
Autores principales: Feng, Xiaodong, Luo, Qingqiong, Zhang, Han, Wang, Han, Chen, Wantao, Meng, Guangxun, Chen, Fuxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479028/
https://www.ncbi.nlm.nih.gov/pubmed/28637493
http://dx.doi.org/10.1186/s13046-017-0553-x

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