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Suppression of MMP-9 by doxycycline in brain arteriovenous malformations

BACKGROUND: The primary aim of this study is to demonstrate the feasibility of utilizing doxycycline to suppress matrix metalloproteinase-9 (MMP-9) in brain arteriovenous malformations (AVMs). METHODS: Ex-vivo treatment of AVM tissues: Intact AVM tissues were treated with doxycycline for 48 hours. A...

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Detalles Bibliográficos
Autores principales:	Hashimoto, Tomoki, Matsumoto, Melissa M, Li, Jenny F, Lawton, Michael T, Young, William L
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC547916/ https://www.ncbi.nlm.nih.gov/pubmed/15667660 http://dx.doi.org/10.1186/1471-2377-5-1

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