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Ratio of Autoantibodies of Tumor Suppressor AIMP2 and Its Oncogenic Variant Is Associated with Clinical Outcome in Lung Cancer

Aminoacyl-tRNA synthetase-interacting multi-functional protein 2 (AIMP2) works as potent tumor suppressor, while its splicing variant lacking exon 2 (AIMP2-DX2) competes with AIMP2 for binding to target proteins and compromises its anti-tumor activity. Assuming that AIMP2 and its variant AIMP2-DX2 c...

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Detalles Bibliográficos
Autores principales: Jung, Ji Ye, Kim, Eun Young, Kim, Arum, Chang, Joon, Kwon, Nam Hoon, Moon, Youngji, Kang, Eun Joo, Sung, Jun Sik, Shim, Hyunbo, Kim, Sunghoon, Chang, Yoon Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479239/
https://www.ncbi.nlm.nih.gov/pubmed/28638448
http://dx.doi.org/10.7150/jca.18450