Targeting TPX2 Suppresses the Tumorigenesis of Hepatocellular Carcinoma Cells Resulting in Arrested Mitotic Phase Progression and Increased Genomic Instability

Hepatocellular carcinoma (HCC) remains one of the most difficult cancers to treat, with chemotherapies being relatively ineffective. Therefore, a better knowledge of molecular hepatocarcinogenesis will provide opportunities for designing targeted therapies. TPX2 (targeting protein for Xklp2) is over...

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Detalles Bibliográficos
Autores principales: Hsu, Chao-Wen, Chen, Yu-Chia, Su, Hsing-Hao, Huang, Guan-Jin, Shu, Chih-Wen, Wu, Tony Tong-Lin, Pan, Hung-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479243/
https://www.ncbi.nlm.nih.gov/pubmed/28638452
http://dx.doi.org/10.7150/jca.17478

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