CD8(+) memory T-cell inflation renders compromised CD4(+) T-cell-dependent CD8(+) T-cell immunity via naïve T-cell anergy

Whether inflation of CD8(+) memory T (mT) cells, which is often derived from repeated prime-boost vaccinations or chronic viral infections in the elderly, would affect late CD8(+) T-cell immunity is a long-standing paradox. We have previously established an animal model with mT-cell inflation by tra...

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Detalles Bibliográficos
Autores principales: Xu, Aizhang, Freywald, Andrew, Xie, Yufeng, Li, Zejun, Xiang, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479263/
https://www.ncbi.nlm.nih.gov/pubmed/28670575
http://dx.doi.org/10.2147/ITT.S131662

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