A Look Inside of the Complex Pathogenesis of B-RAF(V600E)-Driven Cancer

Cancer is a very complex disease, where cell alterations (i.e. gene mutations, dysregulated signaling pathway(s) and epigenetic modifications) contribute to its development and progression. Elucidating the connections among these cell modifications is a critical challenge, in order to understand the...

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Detalles Bibliográficos
Autor principal: Caputo, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479289/
https://www.ncbi.nlm.nih.gov/pubmed/28638488
http://dx.doi.org/10.7150/thno.20460
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author Caputo, Emilia
author_facet Caputo, Emilia
author_sort Caputo, Emilia
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description Cancer is a very complex disease, where cell alterations (i.e. gene mutations, dysregulated signaling pathway(s) and epigenetic modifications) contribute to its development and progression. Elucidating the connections among these cell modifications is a critical challenge, in order to understand the mechanisms which are activated from cancer cells to survive and proliferate. Interesting, Prof. Peng Hou and colleagues, at the First Affiliated Hospital of Xi'an Jiaotong University in China, identified unknown epigenetic mechanisms and their involvement in the tumorigenesis of B-RAF(V600E)-driven cancer.
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spelling pubmed-54792892017-06-21 A Look Inside of the Complex Pathogenesis of B-RAF(V600E)-Driven Cancer Caputo, Emilia Theranostics Editorial Cancer is a very complex disease, where cell alterations (i.e. gene mutations, dysregulated signaling pathway(s) and epigenetic modifications) contribute to its development and progression. Elucidating the connections among these cell modifications is a critical challenge, in order to understand the mechanisms which are activated from cancer cells to survive and proliferate. Interesting, Prof. Peng Hou and colleagues, at the First Affiliated Hospital of Xi'an Jiaotong University in China, identified unknown epigenetic mechanisms and their involvement in the tumorigenesis of B-RAF(V600E)-driven cancer. Ivyspring International Publisher 2017-05-26 /pmc/articles/PMC5479289/ /pubmed/28638488 http://dx.doi.org/10.7150/thno.20460 Text en © Ivyspring International Publisher This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Editorial
Caputo, Emilia
A Look Inside of the Complex Pathogenesis of B-RAF(V600E)-Driven Cancer
title A Look Inside of the Complex Pathogenesis of B-RAF(V600E)-Driven Cancer
title_full A Look Inside of the Complex Pathogenesis of B-RAF(V600E)-Driven Cancer
title_fullStr A Look Inside of the Complex Pathogenesis of B-RAF(V600E)-Driven Cancer
title_full_unstemmed A Look Inside of the Complex Pathogenesis of B-RAF(V600E)-Driven Cancer
title_short A Look Inside of the Complex Pathogenesis of B-RAF(V600E)-Driven Cancer
title_sort look inside of the complex pathogenesis of b-raf(v600e)-driven cancer
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479289/
https://www.ncbi.nlm.nih.gov/pubmed/28638488
http://dx.doi.org/10.7150/thno.20460
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