Making Meaningful Clinical Use of Biomarkers

This review discusses the current state of biomarker discovery for the purposes of diagnostics and therapeutic monitoring. We underscore relevant challenges that have defined the gap between biomarker discovery and meaningful clinical use. We highlight recent advancements in and propose a way to thi...

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Detalles Bibliográficos
Autores principales: Selleck, Matthew J, Senthil, Maheswari, Wall, Nathan R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479428/
https://www.ncbi.nlm.nih.gov/pubmed/28659713
http://dx.doi.org/10.1177/1177271917715236
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author Selleck, Matthew J
Senthil, Maheswari
Wall, Nathan R
author_facet Selleck, Matthew J
Senthil, Maheswari
Wall, Nathan R
author_sort Selleck, Matthew J
collection PubMed
description This review discusses the current state of biomarker discovery for the purposes of diagnostics and therapeutic monitoring. We underscore relevant challenges that have defined the gap between biomarker discovery and meaningful clinical use. We highlight recent advancements in and propose a way to think about future biomarker development.
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spelling pubmed-54794282017-06-28 Making Meaningful Clinical Use of Biomarkers Selleck, Matthew J Senthil, Maheswari Wall, Nathan R Biomark Insights Review This review discusses the current state of biomarker discovery for the purposes of diagnostics and therapeutic monitoring. We underscore relevant challenges that have defined the gap between biomarker discovery and meaningful clinical use. We highlight recent advancements in and propose a way to think about future biomarker development. SAGE Publications 2017-06-19 /pmc/articles/PMC5479428/ /pubmed/28659713 http://dx.doi.org/10.1177/1177271917715236 Text en © The Author(s) 2017 This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
Selleck, Matthew J
Senthil, Maheswari
Wall, Nathan R
Making Meaningful Clinical Use of Biomarkers
title Making Meaningful Clinical Use of Biomarkers
title_full Making Meaningful Clinical Use of Biomarkers
title_fullStr Making Meaningful Clinical Use of Biomarkers
title_full_unstemmed Making Meaningful Clinical Use of Biomarkers
title_short Making Meaningful Clinical Use of Biomarkers
title_sort making meaningful clinical use of biomarkers
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479428/
https://www.ncbi.nlm.nih.gov/pubmed/28659713
http://dx.doi.org/10.1177/1177271917715236
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