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Specific correlation between the major chromosome 10q26 haplotype conferring risk for age-related macular degeneration and the expression of HTRA1

PURPOSE: A region within chromosome 10q26 has a set of single nucleotide polymorphisms (SNPs) that define a haplotype that confers high risk for age-related macular degeneration (AMD). We used a bioinformatics approach to search for genes in this region that may be responsible for risk for AMD by as...

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Detalles Bibliográficos
Autores principales: Liao, Sha-Mei, Zheng, Wei, Zhu, Jiang, Lewis, Casey A., Delgado, Omar, Crowley, Maura A., Buchanan, Natasha M., Jaffee, Bruce D., Dryja, Thaddeus P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479693/
https://www.ncbi.nlm.nih.gov/pubmed/28659708