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Expression of the Human Herpesvirus 6A Latency-Associated Transcript U94A Disrupts Human Oligodendrocyte Progenitor Migration

Progression of demyelinating diseases is caused by an imbalance of two opposing processes: persistent destruction of myelin and myelin repair by differentiating oligodendrocyte progenitor cells (OPCs). Repair that cannot keep pace with destruction results in progressive loss of myelin. Viral infecti...

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Detalles Bibliográficos
Autores principales: Campbell, Andrew, Hogestyn, Jessica M., Folts, Christopher J., Lopez, Brittany, Pröschel, Christoph, Mock, David, Mayer-Pröschel, Margot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479784/
https://www.ncbi.nlm.nih.gov/pubmed/28638124
http://dx.doi.org/10.1038/s41598-017-04432-y