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miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer
The epithelial-mesenchymal transition (EMT) contributes to various processes in cancer progression, such as metastasis and drug resistance. Since we have already established a cell-based reporter system for identifying EMT-suppressive microRNAs (miRNAs) in the pancreatic cancer cell line Panc1, we p...
Autores principales: | Hiramoto, Hidekazu, Muramatsu, Tomoki, Ichikawa, Daisuke, Tanimoto, Kousuke, Yasukawa, Satoru, Otsuji, Eigo, Inazawa, Johji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479822/ https://www.ncbi.nlm.nih.gov/pubmed/28638102 http://dx.doi.org/10.1038/s41598-017-04191-w |
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