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A novel and effective method to generate human porcine-specific regulatory T cells with high expression of IL-10, TGF-β1 and IL-35

Organ transplantation remains the most effective treatment for patients with late stage organ failure. Transgenic pigs provide an alternative organ donor source to the limited availability of human organs. However, cellular rejection still remains to be the obstacle for xenotransplantation. Superior...

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Detalles Bibliográficos
Autores principales: Li, Mingqian, Eckl, Judith, Geiger, Christiane, Schendel, Dolores J., Pohla, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479824/
https://www.ncbi.nlm.nih.gov/pubmed/28638110
http://dx.doi.org/10.1038/s41598-017-04322-3