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A screen for inhibitory peptides of hepatitis C virus identifies a novel entry inhibitor targeting E1 and E2

Hepatitis C virus (HCV) entry into hepatocytes is a multistep process that represents a promising target for antiviral intervention. The viral envelope protein E1E2 plays a critical role in HCV entry. In this study, we sought to identify peptide inhibitors of HCV by screening a library of overlappin...

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Detalles Bibliográficos
Autores principales: Yin, Peiqi, Zhang, Ling, Ye, Fei, Deng, Yao, Lu, Sha, Li, Yi-Ping, Zhang, Leiliang, Tan, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479846/
https://www.ncbi.nlm.nih.gov/pubmed/28638089
http://dx.doi.org/10.1038/s41598-017-04274-8

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