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A screen for inhibitory peptides of hepatitis C virus identifies a novel entry inhibitor targeting E1 and E2
Hepatitis C virus (HCV) entry into hepatocytes is a multistep process that represents a promising target for antiviral intervention. The viral envelope protein E1E2 plays a critical role in HCV entry. In this study, we sought to identify peptide inhibitors of HCV by screening a library of overlappin...
Autores principales: | Yin, Peiqi, Zhang, Ling, Ye, Fei, Deng, Yao, Lu, Sha, Li, Yi-Ping, Zhang, Leiliang, Tan, Wenjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479846/ https://www.ncbi.nlm.nih.gov/pubmed/28638089 http://dx.doi.org/10.1038/s41598-017-04274-8 |
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