Heparin Mimics Extracellular DNA in Binding to Cell Surface-Localized Proteins and Promoting Staphylococcus aureus Biofilm Formation

Staphylococcus aureus is a leading cause of catheter-related bloodstream infections. Biofilms form on these implants and are held together by a matrix composed of proteins, polysaccharides, and extracellular DNA (eDNA). Heparin is a sulfated glycosaminoglycan that is routinely used in central venous...

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Detalles Bibliográficos
Autores principales: Mishra, Surabhi, Horswill, Alexander R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480030/
https://www.ncbi.nlm.nih.gov/pubmed/28656173
http://dx.doi.org/10.1128/mSphere.00135-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480030/
https://www.ncbi.nlm.nih.gov/pubmed/28656173
http://dx.doi.org/10.1128/mSphere.00135-17

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