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Methylglyoxal Induces Changes in the Glyoxalase System and Impairs Glutamate Uptake Activity in Primary Astrocytes

The impairment of astrocyte functions is associated with diabetes mellitus and other neurodegenerative diseases. Astrocytes have been proposed to be essential cells for neuroprotection against elevated levels of methylglyoxal (MG), a highly reactive aldehyde derived from the glycolytic pathway. MG e...

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Detalles Bibliográficos
Autores principales:	Hansen, Fernanda, Galland, Fabiana, Lirio, Franciane, de Souza, Daniela Fraga, Da Ré, Carollina, Pacheco, Rafaela Ferreira, Vizuete, Adriana Fernanda, Quincozes-Santos, André, Leite, Marina Concli, Gonçalves, Carlos-Alberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480050/ https://www.ncbi.nlm.nih.gov/pubmed/28685011 http://dx.doi.org/10.1155/2017/9574201

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