Cancer with low cathepsin D levels is susceptible to vacuolar (H(+))‐ATPase inhibition

Vacuolar (H(+))‐ATPases (V‐ATPases) have important roles in the supply of nutrients to tumors by mediating autophagy and the endocytic uptake of extracellular fluids. Accordingly, V‐ATPases are attractive therapeutic targets for cancer. However, the clinical use of V‐ATPase inhibitors as anticancer...

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Detalles Bibliográficos
Autores principales: Kitazawa, Satoshi, Nishizawa, Satoru, Nakagawa, Hideyuki, Funata, Masaaki, Nishimura, Kazuho, Soga, Tomoyoshi, Hara, Takahito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480082/
https://www.ncbi.nlm.nih.gov/pubmed/28317223
http://dx.doi.org/10.1111/cas.13240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480082/
https://www.ncbi.nlm.nih.gov/pubmed/28317223
http://dx.doi.org/10.1111/cas.13240

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