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Ritonavir and ixazomib kill bladder cancer cells by causing ubiquitinated protein accumulation
There is no curative treatment for advanced bladder cancer. Causing ubiquitinated protein accumulation and endoplasmic reticulum stress is a novel approach to cancer treatment. The HIV protease inhibitor ritonavir has been reported to suppress heat shock protein 90 and increase the amount of unfolde...
Autores principales: | Sato, Akinori, Asano, Takako, Okubo, Kazuki, Isono, Makoto, Asano, Tomohiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480085/ https://www.ncbi.nlm.nih.gov/pubmed/28342223 http://dx.doi.org/10.1111/cas.13242 |
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