M2‐like macrophage polarization in high lactic acid‐producing head and neck cancer

Reprogramming of glucose metabolism in tumor cells is referred to as the Warburg effect and results in increased lactic acid secretion into the tumor microenvironment. We have previously shown that lactic acid has important roles as a pro‐inflammatory and immunosuppressive mediator and promotes tumo...

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Detalles Bibliográficos
Autores principales: Ohashi, Toshimitsu, Aoki, Mitsuhiro, Tomita, Hiroyuki, Akazawa, Takashi, Sato, Katsuya, Kuze, Bunya, Mizuta, Keisuke, Hara, Akira, Nagaoka, Hitoshi, Inoue, Norimitsu, Ito, Yatsuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480089/
https://www.ncbi.nlm.nih.gov/pubmed/28370718
http://dx.doi.org/10.1111/cas.13244

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