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Sinonasal teratocarcinosarcoma: a case report

BACKGROUND: Sinonasal teratocarcinosarcoma is a rare and aggressive malignancy with histological features of both carcinosarcoma and teratoma. The optimal management of this malignancy is unclear, with most patients being managed by a combination of surgery and radiotherapy. CASE PRESENTATION: We de...

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Autores principales: Foong, Yi Chao, Murdolo, Vince, Naiman, Nusa, Hepner, Laura, Awad, Raef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480100/
https://www.ncbi.nlm.nih.gov/pubmed/28637513
http://dx.doi.org/10.1186/s13256-017-1327-y
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author Foong, Yi Chao
Murdolo, Vince
Naiman, Nusa
Hepner, Laura
Awad, Raef
author_facet Foong, Yi Chao
Murdolo, Vince
Naiman, Nusa
Hepner, Laura
Awad, Raef
author_sort Foong, Yi Chao
collection PubMed
description BACKGROUND: Sinonasal teratocarcinosarcoma is a rare and aggressive malignancy with histological features of both carcinosarcoma and teratoma. The optimal management of this malignancy is unclear, with most patients being managed by a combination of surgery and radiotherapy. CASE PRESENTATION: We describe an 83-year-old white woman with sinonasal teratocarcinosarcoma of her left nasal cavity treated with surgical debulking initially with radiological evidence of residual disease which was treated with radiotherapy (60 Gy in 30 fractions). A follow-up examination at 2 years showed no evidence of recurrence. CONCLUSIONS: In cases of sinonasal teratocarcinosarcoma with residual disease post-surgery, radiotherapy alone can be an effective option.
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spelling pubmed-54801002017-06-23 Sinonasal teratocarcinosarcoma: a case report Foong, Yi Chao Murdolo, Vince Naiman, Nusa Hepner, Laura Awad, Raef J Med Case Rep Case Report BACKGROUND: Sinonasal teratocarcinosarcoma is a rare and aggressive malignancy with histological features of both carcinosarcoma and teratoma. The optimal management of this malignancy is unclear, with most patients being managed by a combination of surgery and radiotherapy. CASE PRESENTATION: We describe an 83-year-old white woman with sinonasal teratocarcinosarcoma of her left nasal cavity treated with surgical debulking initially with radiological evidence of residual disease which was treated with radiotherapy (60 Gy in 30 fractions). A follow-up examination at 2 years showed no evidence of recurrence. CONCLUSIONS: In cases of sinonasal teratocarcinosarcoma with residual disease post-surgery, radiotherapy alone can be an effective option. BioMed Central 2017-06-22 /pmc/articles/PMC5480100/ /pubmed/28637513 http://dx.doi.org/10.1186/s13256-017-1327-y Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Foong, Yi Chao
Murdolo, Vince
Naiman, Nusa
Hepner, Laura
Awad, Raef
Sinonasal teratocarcinosarcoma: a case report
title Sinonasal teratocarcinosarcoma: a case report
title_full Sinonasal teratocarcinosarcoma: a case report
title_fullStr Sinonasal teratocarcinosarcoma: a case report
title_full_unstemmed Sinonasal teratocarcinosarcoma: a case report
title_short Sinonasal teratocarcinosarcoma: a case report
title_sort sinonasal teratocarcinosarcoma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480100/
https://www.ncbi.nlm.nih.gov/pubmed/28637513
http://dx.doi.org/10.1186/s13256-017-1327-y
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AT awadraef sinonasalteratocarcinosarcomaacasereport