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Asymmetric DNA methylation of CpG dyads is a feature of secondary DMRs associated with the Dlk1/Gtl2 imprinting cluster in mouse

BACKGROUND: Differential DNA methylation plays a critical role in the regulation of imprinted genes. The differentially methylated state of the imprinting control region is inherited via the gametes at fertilization, and is stably maintained in somatic cells throughout development, influencing the e...

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Detalles Bibliográficos
Autores principales: Guntrum, Megan, Vlasova, Ekaterina, Davis, Tamara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480104/
https://www.ncbi.nlm.nih.gov/pubmed/28649282
http://dx.doi.org/10.1186/s13072-017-0138-0