Successful treatment of multidrug resistant Klebsiella pneumoniae using dual carbapenem regimen in immunocompromised patient

This report describes a longitudinal case of immunocompromised patient post kidney transplant who was admitted to our institution repeatedly for treatment of various infections caused by multi-drug resistant Klebsiella pneumoniae. The patient was successfully treated with a combination of ertapenem/...

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Detalles Bibliográficos
Autores principales: El Nekidy, Wasim S., Mooty, Mohamad Y., Attallah, Nizar, Cardona, Lyssette, Bonilla, Maria Fernanda, Ghazi, Islam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480227/
https://www.ncbi.nlm.nih.gov/pubmed/28660131
http://dx.doi.org/10.1016/j.idcr.2017.06.005
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author El Nekidy, Wasim S.
Mooty, Mohamad Y.
Attallah, Nizar
Cardona, Lyssette
Bonilla, Maria Fernanda
Ghazi, Islam M.
author_facet El Nekidy, Wasim S.
Mooty, Mohamad Y.
Attallah, Nizar
Cardona, Lyssette
Bonilla, Maria Fernanda
Ghazi, Islam M.
author_sort El Nekidy, Wasim S.
collection PubMed
description This report describes a longitudinal case of immunocompromised patient post kidney transplant who was admitted to our institution repeatedly for treatment of various infections caused by multi-drug resistant Klebsiella pneumoniae. The patient was successfully treated with a combination of ertapenem/meropenem on multiple occasions despite the elevated MICs. Our observations corroborate previous preclinical studies and case reports showing the efficacy of double carbapenem regimens against resistant Enterobacteriaceae.
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spelling pubmed-54802272017-06-28 Successful treatment of multidrug resistant Klebsiella pneumoniae using dual carbapenem regimen in immunocompromised patient El Nekidy, Wasim S. Mooty, Mohamad Y. Attallah, Nizar Cardona, Lyssette Bonilla, Maria Fernanda Ghazi, Islam M. IDCases Case Report This report describes a longitudinal case of immunocompromised patient post kidney transplant who was admitted to our institution repeatedly for treatment of various infections caused by multi-drug resistant Klebsiella pneumoniae. The patient was successfully treated with a combination of ertapenem/meropenem on multiple occasions despite the elevated MICs. Our observations corroborate previous preclinical studies and case reports showing the efficacy of double carbapenem regimens against resistant Enterobacteriaceae. Elsevier 2017-06-15 /pmc/articles/PMC5480227/ /pubmed/28660131 http://dx.doi.org/10.1016/j.idcr.2017.06.005 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
El Nekidy, Wasim S.
Mooty, Mohamad Y.
Attallah, Nizar
Cardona, Lyssette
Bonilla, Maria Fernanda
Ghazi, Islam M.
Successful treatment of multidrug resistant Klebsiella pneumoniae using dual carbapenem regimen in immunocompromised patient
title Successful treatment of multidrug resistant Klebsiella pneumoniae using dual carbapenem regimen in immunocompromised patient
title_full Successful treatment of multidrug resistant Klebsiella pneumoniae using dual carbapenem regimen in immunocompromised patient
title_fullStr Successful treatment of multidrug resistant Klebsiella pneumoniae using dual carbapenem regimen in immunocompromised patient
title_full_unstemmed Successful treatment of multidrug resistant Klebsiella pneumoniae using dual carbapenem regimen in immunocompromised patient
title_short Successful treatment of multidrug resistant Klebsiella pneumoniae using dual carbapenem regimen in immunocompromised patient
title_sort successful treatment of multidrug resistant klebsiella pneumoniae using dual carbapenem regimen in immunocompromised patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480227/
https://www.ncbi.nlm.nih.gov/pubmed/28660131
http://dx.doi.org/10.1016/j.idcr.2017.06.005
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