Use of costic acid, a natural extract from Dittrichia viscosa, for the control of Varroa destructor, a parasite of the European honey bee

Costic acid has been isolated from the plant Dittrichia viscosa and its efficacy against Varroa destructor, a parasite of Apis mellifera, the European honey bee, has been studied. Costic acid exhibited potent in vivo acaricidal activity against the parasite. Initial experiments showed that the compo...

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Autores principales: Sofou, Kalliopi, Isaakidis, Demosthenis, Spyros, Apostolos, Büttner, Anita, Giannis, Athanassios, Katerinopoulos, Haralambos E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480341/
https://www.ncbi.nlm.nih.gov/pubmed/28684976
http://dx.doi.org/10.3762/bjoc.13.96
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author Sofou, Kalliopi
Isaakidis, Demosthenis
Spyros, Apostolos
Büttner, Anita
Giannis, Athanassios
Katerinopoulos, Haralambos E
author_facet Sofou, Kalliopi
Isaakidis, Demosthenis
Spyros, Apostolos
Büttner, Anita
Giannis, Athanassios
Katerinopoulos, Haralambos E
author_sort Sofou, Kalliopi
collection PubMed
description Costic acid has been isolated from the plant Dittrichia viscosa and its efficacy against Varroa destructor, a parasite of Apis mellifera, the European honey bee, has been studied. Costic acid exhibited potent in vivo acaricidal activity against the parasite. Initial experiments showed that the compound is not toxic for human umbilical vein endothelial cells (HUVEC) at concentrations of up to 230 micromolar (μM), indicating that costic acid could be used as a safe, low-cost and efficient agent for controlling varroosis in honey bee colonies.
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spelling pubmed-54803412017-07-06 Use of costic acid, a natural extract from Dittrichia viscosa, for the control of Varroa destructor, a parasite of the European honey bee Sofou, Kalliopi Isaakidis, Demosthenis Spyros, Apostolos Büttner, Anita Giannis, Athanassios Katerinopoulos, Haralambos E Beilstein J Org Chem Full Research Paper Costic acid has been isolated from the plant Dittrichia viscosa and its efficacy against Varroa destructor, a parasite of Apis mellifera, the European honey bee, has been studied. Costic acid exhibited potent in vivo acaricidal activity against the parasite. Initial experiments showed that the compound is not toxic for human umbilical vein endothelial cells (HUVEC) at concentrations of up to 230 micromolar (μM), indicating that costic acid could be used as a safe, low-cost and efficient agent for controlling varroosis in honey bee colonies. Beilstein-Institut 2017-05-18 /pmc/articles/PMC5480341/ /pubmed/28684976 http://dx.doi.org/10.3762/bjoc.13.96 Text en Copyright © 2017, Sofou et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Sofou, Kalliopi
Isaakidis, Demosthenis
Spyros, Apostolos
Büttner, Anita
Giannis, Athanassios
Katerinopoulos, Haralambos E
Use of costic acid, a natural extract from Dittrichia viscosa, for the control of Varroa destructor, a parasite of the European honey bee
title Use of costic acid, a natural extract from Dittrichia viscosa, for the control of Varroa destructor, a parasite of the European honey bee
title_full Use of costic acid, a natural extract from Dittrichia viscosa, for the control of Varroa destructor, a parasite of the European honey bee
title_fullStr Use of costic acid, a natural extract from Dittrichia viscosa, for the control of Varroa destructor, a parasite of the European honey bee
title_full_unstemmed Use of costic acid, a natural extract from Dittrichia viscosa, for the control of Varroa destructor, a parasite of the European honey bee
title_short Use of costic acid, a natural extract from Dittrichia viscosa, for the control of Varroa destructor, a parasite of the European honey bee
title_sort use of costic acid, a natural extract from dittrichia viscosa, for the control of varroa destructor, a parasite of the european honey bee
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480341/
https://www.ncbi.nlm.nih.gov/pubmed/28684976
http://dx.doi.org/10.3762/bjoc.13.96
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